based on genome-wide RNA interference screeningbased on genome-wide RNA interference screeningbased on genome-wide RNA interference screeningbased on genome-wide RNA interference screeningbased on genome-wide RNA interference screeningbased on genom
Modern biology has become an information science. Since the invention of a DNA sequencing method by Sanger in the late seventies, public repositories of genomic sequences have been growing exponentially, doubling in size every 16 months—a rate often
Matlab's implementation of Fisher's exact test only supports one-tailed tests. Other implementations on the file exchange are reportedly buggy and are far too slow for problems I'm working on. This implementation does 2.5e6 one or two-tailed tests p
Gene expression patterns hold valuable information regarding the specific functions of particular cell and tissue types. Initially, the analysis of transcr ipts was limited to testing changes in expression of only a few genes at a time using low-thr
Automated annotation of protein function is challenging. As the number of sequenced genomes rapidly grows, the vast majority of proteins can only be annotated computationally. Nature often brings several domains together to form multi-domain and mult
