I. Introduction........................................................................ 3 II. Transcr iptomics.................................................................... 4 III. Proteomics Methodologies for Biomarker Discovery...............
MicroRNAs are fine tuners of diverse biological responses and are expressed in various cell ty of the liver. Here we hypothesized that circulating microRNAs (miRNAs) may serve as biomarkers of liver damage and inflammation. We studied miRNA-122 that
Functional near-infrared spectroscopy (fNIRS) is a neuroimaging technology which is suitable for psychiatric patients. Several fNIRS studies have found abnormal brain activations during cognitive tasks in elderly depression. In this paper, we propose
NAD+/NADH redox state has been implicated in many diseases such as cancer and diabetes as well as in the regulation of embryonic development and aging. To fluorimetrically assess the mitochondrial redox state, Dr. Chance and co-workers measured the f
The research target is to explore the key biomarkersof colorectal cancer by studying the impact of dietary factors oncolorectal cancer. We employed statistical methods to preprocess<span style="color:#000000;fo
Computationally identifying effective biomarkers for cancers from gene expression profiles is an important and challenging task. The challenge lies in the complicated pathogenesis of cancers that often involve the dysfunction of many genes and regula
Background: Acupuncture has been practiced in China for thousands of years as part of the Traditional Chinese Medicine (TCM) and has gradually accepted in western countries as an alternative or complementary treatment. However, the underlying mechani
Pulse diagnosis, recognized as an important branch of Traditional Chinese Medicine (TCM), has a long history for health diagnosis. Certain features in the pulse are known to be related with the physiological status, which have been id
Discovery and validation of immune-associated long non-coding RNA biomarkers associated with clinically molecular subtype and prognosis in diffuse large B cell lymphoma
Collagen is an endogenous fluorophore that accounts for about 70% of all proteins of human skin, so it can be an optical marker for structural abnormalities in tissues registered by laser fluorescent diagnostics in vivo. Using the examples of such ab
